Research and Studies
Hormone Replacement
- Bhasin S, Brito JP, Cunningham GR, et al. Testosterone therapy in men with hypogonadism: An Endocrine Society clinical practice guideline. J Clin Endocrinol Metab. 2018;103(5):1715-1744. doi:10.1210/jc.2018-00229.
- Davis SR, Baber R, Panay N, et al. Global Consensus Position Statement on the use of testosterone therapy for women. J Clin Endocrinol Metab. 2019;104(10):4660-4666. doi:10.1210/jc.2019-01603.
- Ganesan K, Habboush Y, Sultan S. Transdermal testosterone in female hypoactive sexual desire disorder: A rapid qualitative systematic review using GRADE. Cureus. 2018;10(3):e2401. doi:10.7759/cureus.2401.
- Grossmann M, Anawalt BD, Yeap BB. Testosterone therapy in older men: Clinical implications of recent landmark trials. Eur J Endocrinol. 2024;190(1):R1-R17. doi:10.1530/EJE-23-0833.
- Lincoff AM, Bhasin S, Flevaris P, et al. Cardiovascular safety of testosterone-replacement therapy. N Engl J Med. 2023;389(24):2237-2249. doi:10.1056/NEJMoa2301628.
- Parish SJ, Simon JA, Davis SR, et al. International Society for the Study of Women’s Sexual Health clinical practice guideline for the use of systemic testosterone for hypoactive sexual desire disorder in women. J Sex Med. 2021;18(5):849-867. doi:10.1016/j.jsxm.2020.10.009.
NAD+ and Related
- Elhassan YS, Kluckova K, Fletcher RS, et al. Nicotinamide riboside augments the aged human skeletal muscle NAD+ metabolome and induces transcriptomic and anti-inflammatory signatures. Cell Rep. 2019;28(7):1717-1728.e6. doi:10.1016/j.celrep.2019.07.043.
- Freeberg KA, Craighead DH, Seals DR. Nicotinamide riboside supplementation for treating elevated systolic blood pressure and arterial stiffness in midlife and older adults: Rationale and design of a randomized, double-blind, placebo-controlled clinical trial. Front Cardiovasc Med. 2022;9:881703. doi:10.3389/fcvm.2022.881703.
- Martens CR, Denman BA, Mazzo MR, et al. Chronic nicotinamide riboside supplementation is well tolerated and elevates NAD+ in healthy middle-aged and older adults. Nat Commun. 2018;9:1286. doi:10.1038/s41467-018-03421-7.
- Orr ME, Chuang JC, Liu C-S, et al. Nicotinamide riboside for treating mild cognitive impairment: A randomized, double-blind, placebo-controlled trial. EClinicalMedicine. 2024;68:103973. doi:10.1016/j.eclinm.2024.103973.
Peptides
- Beck DE, Sweeney WB, McCarter MD; Ipamorelin 201 Study Group. Prospective, randomized, controlled, proof-of-concept study of the ghrelin mimetic ipamorelin for the management of postoperative ileus in bowel resection patients. Int J Colorectal Dis. 2014;29(12):1527-1534. doi:10.1007/s00384-014-2030-8.
- Lee E, Padgett B. Intra-articular injection of BPC-157 for multiple types of knee pain: A pilot study. Altern Ther Health Med. 2021;27(4):8-13.
- Lee E, Walker C, Ayadi B. Effect of BPC-157 on symptoms in patients with interstitial cystitis: A pilot study. Altern Ther Health Med. 2024;30(10):12-17.
- Lee E, Burgess K. Safety of intravenous infusion of BPC-157 in humans: A pilot study. Altern Ther Health Med. 2025;31(5):20-24.
- McGuire FP, Martinez R, Lenz A, Skinner L, Cushman DM. Regeneration or risk? A narrative review of BPC-157 for musculoskeletal healing. Curr Rev Musculoskelet Med. 2025;18(4):611-619. doi:10.1007/s12178-025-09990-7.
